Date	Event	Description
29 July 2011	New citation required but conclusions have not changed	One new trial has been included, and the text has been amended accordingly. The conclusions remain the same. The editorial group is aware that a clinical trial by Prof. Joachim Boldt has been found to have been fabricated (Boldt 2009). As the editors who revealed this fabrication point out (Reinhart 2011; Shafer 2011), this casts some doubt on the veracity of other studies by the same author. One trial by Prof. Boldt is included in this review (Boldt 1993), but there were no deaths in the trial and so the data do not contribute to the results. The inclusion of the trial has no impact on the conclusions of the review. The authors of the review have changed.
14 October 2008	New search has been performed	Five new trials have been included in the review, and the analysis, results and discussion sections have been amended accordingly.