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. 2011 Nov 9;2011(11):CD001208. doi: 10.1002/14651858.CD001208.pub4

Greenhalgh 1995.

Methods Method of random allocation not described. Author contacted and confirmed the use of a randomisation scheme controlled by the pharmacy.
Participants Patients aged 18 years or younger with acute burns.
Interventions 1) High albumin group (n=34): Patients were supplemented with human albumin to maintain serum levels between 2.5 and 3.5g/dL. Albumin was supplied as a continuous drip of 25% human albumin at a rate of 3‐10mL/hour. Supplementation was discontinued if serum albumin levels remained >2.5 g/dL without supplementation or if intravenous support was discontinued. 
 2) Low albumin group (n=36): Patients were not given albumin supplementation unless levels dropped <1.5 g/dL. During burn shock, patients were allowed to receive albumin if they had levels <2.0 g/dL and were receiving >4 mL/Kg/% burn fluid resuscitation.
Outcomes Deaths reported.
Notes Follow‐up to discharge.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment (selection bias) Low risk