Greenhalgh 1995.
Methods | Method of random allocation not described. Author contacted and confirmed the use of a randomisation scheme controlled by the pharmacy. | |
Participants | Patients aged 18 years or younger with acute burns. | |
Interventions | 1) High albumin group (n=34): Patients were supplemented with human albumin to maintain serum levels between 2.5 and 3.5g/dL. Albumin was supplied as a continuous drip of 25% human albumin at a rate of 3‐10mL/hour. Supplementation was discontinued if serum albumin levels remained >2.5 g/dL without supplementation or if intravenous support was discontinued. 2) Low albumin group (n=36): Patients were not given albumin supplementation unless levels dropped <1.5 g/dL. During burn shock, patients were allowed to receive albumin if they had levels <2.0 g/dL and were receiving >4 mL/Kg/% burn fluid resuscitation. | |
Outcomes | Deaths reported. | |
Notes | Follow‐up to discharge. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment (selection bias) | Low risk |