| Methods |
Unblinded, randomised, controlled trial. |
| Participants |
Kenyan children older than 2 months with symptomatic sever malarial anaemia (haemoglobin less than 5g/dl). |
| Interventions |
1) Intervention (n=23) received 4.5% albumin.
2) Intervention (n=20) received 0.9% saline.
3) Control (n=18) received only maintenance (rescue emergency intervention when required). |
| Outcomes |
Change in perfusion rates. Deaths not reported. |
| Notes |
|
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment (selection bias) |
Low risk |
"On admission to the HDU, children were randomly assigned to PTM with one of the three treatments using sealed card system. The sealed cards were available 24h/day; either the admitting doctor or nurse assigned the therapy at admission based on laboratory results or, in an emergency, on clinical suspicion." p. 128. |
