Study	Reason for exclusion
Artru 1989	Intervention to control intracranial pressure not directed at fluid resuscitation.
Bellomo 2006	Trial was subset of SAFE 2004 trial, thus offering no new data.
Brehme 1993	Intervention directed at haemodilution, not at volume replacement.
Carlon 1979	Randomised controlled trial of pre‐operative volume expansion during anaesthesia.
Fiorica 1991	Not a randomised trial. The first 18 patients received standard maintenance crystalloid solution. The next 10 consecutive patients received 100g of a concentrated 25% albumin solution.
Goslinga 1992	Intervention directed at haemodilution, not volume replacement.
Grundmann 1985	This was a randomised controlled trial of 220 patients, 106 were given albumin when their colloid osmotic pressure (COP) fell below 24 cm water and 114 were given albumin when their COP fell below 29 cm water. Patients were not randomised to albumin or no albumin, nor were they randomised to supplemental albumin versus normal amounts of albumin, rather, this was a trial of different criteria for albumin supplementation. It is unlikely therefore that the two arms of the trial were comparable and hence the trial is excluded.
Grundmann 1986	This was a randomised controlled trial to examine whether postoperative human albumin supply is justified in intensive care patients in the case that the colloid osmotic pressure decreases below 26 centimetres of water. The therapy group received human albumin only if the colloid osmotic pressure dropped below 26 cm water. The control group also received albumin but only for resuscitation of cardiac output and central venous pressure. The trial was excluded because both intervention and control groups received albumin.
Hauser 1980	Cross‐over trial.
Lagonidis 1995	Intervention was pre‐loading for coronary artery bypass surgery.
Lennihan 2000	Participants had suffered subarachnoid hemorrhage and therefore did not meet the inclusion criteria.
Magder 1999	Participants were stable patients following cardiopulmonary bypass surgery and therefore did not meet the inclusion criteria.
Maitland 2005a	Trial was subset of SAFE 2004 trial, thus offering no new data.
Martin 1999	Intervention involved comparison of albumin with furosemide verus placebo therefore did not meet the inclusion criteria.
Metildi 1984	Participants were admissions to an intensive care and a trauma unit with adult respiratory distress syndrome and established pulmonary failure. Included both trauma and non‐trauma patients and therefore did not meet the inclusion criteria for the review.
Steinberg 1989	Cross‐over trial.
Tomita 1994	Randomised controlled trial of normal versus high oncotic pressure following head injury. Patients were not randomised to albumin or no albumin. Albumin and furosemide were used together to achieve high oncotic pressure.