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. 2020 Mar 4;10:3974. doi: 10.1038/s41598-020-60212-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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miRNA expression in mCRC patients and healthy donors: Extracellular vesicles (EVs) from metastatic colorectal cancer (mCRC) patients showed higher expression of miR-19b, 200b, 21, 222 and 92a in comparison to those of healthy donors. Data are presented as a box and whiskers plots (min to max). Mann-Whitney U test was used: *p < 0.05, **p < 0.01, ***p < 0.001, ns: no significant differences.