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. 2020 Mar 4;10:3974. doi: 10.1038/s41598-020-60212-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Kaplan-Meier curves of PFS and OS according to miR-92a and miR-222 expression: (A) Progression-free survival (PFS) probability curves according to lower and higher expression of miR-92 at 12 weeks (12w) showing increased DFS in the lower expression group but no statistical differences. (B) Overall survival (OS) probability curves according to lower and higher expression of miR-222 at 24 weeks (24w) are statistically different. (C) Overall survival (OS) probability curves according to lower and higher expression of miR-92 (24w) showing 2 separated curves but with non-statistically significant differences. Log-rank test was used. p = p-value.