Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 26;11:230. doi: 10.3389/fimmu.2020.00230

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Makinde, Winter, Procissi, Mike, Stock, Kando, Gadhvi, Droho, Bloomfield, Dominguez, Mayr, Lavine, Putterman and Cuda.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Expression of “NP-SLE” and “DAM” signatures correlates with behavioral deficits in young CReCOM mice. FACS-purified microglia of 5-6-month-old and 11-12-month-old female WT (n = 4) and CReCOM mice (n = 4) mice were analyzed by RNA-seq. Correlation coefficients (R) were determined between behavior (y-axis) and gene expression (x-axis) scores. Lines suggest pattern of correlation. Scatter plots depicting correlation between (A) “NP-SLE signature” or (B) downregulated and upregulated “DAM signature” gene expression scores and behavior scores.