Figure 12.

Example of altered cerebral–cerebellar functional connectivity due to a congenital lesion in the cerebral hemisphere. This patient has schizencephaly in the right primary somatomotor region (arrow) (a, b). BOLD activity on motor tasks indicates that both right and left somatomotor function (red = bilateral finger task with alternating sides, green = tongue task, blue = lip task) is served by the anatomically normal left cerebral hemisphere (a, b). There was no evidence of neurovascular uncoupling in the right cerebral hemisphere (not shown). Corresponding BOLD activity is present in the right cerebellar hemisphere, with bilateral finger tapping depicted (red) (c). There was no appreciable BOLD activity in the expected somatomotor areas of the right cerebral or left cerebellar hemispheres. BOLD,blood oxygen level dependent.