Figure 3.

Key sagittal MPRAGE views of the cerebellum, medial to lateral at 3 T (a–d) and 7T (e–f). Near-midline sagittal view demonstrates the vermis in native (a) and color-coded, enumerated (b) formats. The deep midline primary (light blue) and pre-pyramidal/pre-biventral (dark blue) fissures are prominent features of a normal vermis. The primary fissure separates the anterior lobe (lobules I–V) from the posterior lobe (lobules VI–IX, with lobule X constituting the flocculonodular lobe); note that the ‘anterior’ lobe is actually positioned superior to the posterior lobe by conventional directions used in clinical interpretation. A common dorsally directed white matter stem (red line) gives rise to lobules VI and VIIA/VIIB, whereas the remaining lobules of the vermis typically have unique white matter stems. In the mid-aspect of the cerebellar hemisphere, the primary fissure is shallow and anteriorly positioned, consistent with relatively small and medial configuration of the anterior lobe (c). The white matter stems of the Crus I (yellow) and Crus II (light blue) are clearly distinguishable. The superior posterior and horizontal fissures bracket Crus I. The far lateral aspect of the cerebellar hemisphere is composed of the Crus I/Crus II expansions along with lobule VIIB (d). The superior posterior and horizontal fissures remain clearly visible and converge anteriorly. Sagittal images in another patient at 7 T demonstrates a very similar appearance of the lobules and major fissures of the vermis (e) and the lateral cerebellar hemisphere (f) with only minor differences compared to the first patient, illustrating that these features are reasonably reproducible. Although the fine detail of the lobules and fissures are better depicted at 7 T, note that the main features are also readily identifiable at 3 T. MPRAGE, magnetization-prepared rapid acquisition with gradient echo.