Fig. 5. Inhibition of autophagy by chloroquine abolished the upregulation of arterial TGF-β1, TGF-β3, RUNX2 and ALP expression in KL+/− mice.
(A) Western blots analysis of TGF-β1, TGF-β3, RUNX2 and ALP protein expression. (B) Quantification of TGF-β1 protein levels. (C) Quantification of TGF-β3 protein levels. (D) Quantification of RUX2 protein levels. (E) Quantification of ALP1 protein levels. Data are expressed as means ± SE and analyzed by one-way ANOVA. n=4. **p<0.01 vs WT mice; ##p<0.01 vs KL (+/−)-CON mice.