Figure 4: Pulmonary inflammation was reduced by protective donor plasma.
Mice underwent 90 minutes of hemorrhagic shock followed by resuscitation with 1x shed blood of the more protective plasma or the less protective plasma and compared to mice with no resuscitation (HS only) or sham. Myeloperoxidase immunostaining was assessed as an indicator of neutrophil infiltration. Shown are representative images and the corresponding quantitation. Data is reported as mean ± SD with n=6–7/group and was analyzed by one-way ANOVA with Bonferroni post hoc. Abbreviations: HS=hemorrhagic shock only/no resuscitation, MPP=more protective plasma, LPP=less protective plasma.