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. Author manuscript; available in PMC: 2020 Sep 18.
Published in final edited form as: J Am Chem Soc. 2019 Sep 9;141(37):14864–14869. doi: 10.1021/jacs.9b07875

Table 3.

Enantioconvergent N-alkylation: Scope with respect to the nucleophile.

graphic file with name nihms-1557306-t0008.jpg
entry H-amine ee (%) yield (%)a
1 graphic file with name nihms-1557306-t0009.jpg 96 66
2 98 69
3 graphic file with name nihms-1557306-t0010.jpg 83 52
4 90 84
5 87 94
6 87 54
7 graphic file with name nihms-1557306-t0011.jpg 90 84
8 88 70
9 graphic file with name nihms-1557306-t0012.jpg 84 56
10 graphic file with name nihms-1557306-t0013.jpg 91 58
11 graphic file with name nihms-1557306-t0014.jpg 84 53
12 graphic file with name nihms-1557306-t0015.jpg 96 82
13 graphic file with name nihms-1557306-t0016.jpg 94 80
14 graphic file with name nihms-1557306-t0017.jpg 88 64

All data represent the average of two experiments.

a

Yield of purified product.