TABLE 3.
Associations of Child and Adult Adiposity Measures with Semen Outcomes at Mean Age 44 Years
| Sperm Concentrationa (×103/mL) Bb (95% CI) |
<15 Million Sperm/mL ORb (95% CI) |
Percent Progressive Motility B (95% CI) |
<32% Progressive Motility OR (95% CI) |
Percent Normal Morphology B (95% CI) |
<4% Normal Morphology OR (95% CI) |
|
|---|---|---|---|---|---|---|
| wt/ht 4 monthsc | n = 153 | n = 153 | n = 153 | n = 153 | n = 152 | n = 152 |
| Continuous | 0.0005 (−0.02, 0.02) | 1.0 (0.98, 1.0) | 0.03 (−0.07, 0.14) | 1.0 (0.98, 1.0) | 0.01 (−0.02, 0.03) | 1.0 (0.99, 1.0) |
| ≥85th vs. <85th percentile | 0.33 (−0.97. 1.6) | 0.60 (0.13, 2.9) | −1.6 (−8.9, 5.6) | 0.93 (0.36, 2.4) | 1.2 (−0.54, 2.9 | 0.70 (0.26, 1.9) |
| wt/ht 12 monthsc | n = 152 | n = 152 | n = 152 | n = 152 | n = 151 | n = 151 |
| Continuous | 0.01 (−0.01, 0.03) | 1.0 (0.98, 1.0) | 0.02 (−0.07, 0.12) | 1.0 (0.99, 1.0) | 0.01 (−0.02, 0.03) | 1.0 (0.99, 1.0) |
| ≥85th vs. <85th percentile | −0.14 (−1.3, 0.99) | 1.6 (0.56, 4.8) | 1.4 (−6.2, 9.1) | 0.77 (0.28, 2.2) | 0.48 (−0.91, 1.9) | 1.3 (0.61, 2.9) |
| ssBMI 4 years | n = 160 | n = 160 | n = 160 | n = 160 | n = 159 | n = 159 |
| Continuous | 0.003 (−0.02, 0.02) | 1.0 (0.98, 1.0) | −0.01 (−0.10, 0.08) | 1.0 (0.99, 1.0) | 0.004 (−0.02, 0.03) | 1.0 (0.99, 1.0) |
| ≥85th vs. <85th percentile | −0.12 (−2.3, −0.03) | 1.7 (0.55, 5.0) | −3.3 (−8.9, 2.3) | 1.4 (0.67, 2.8) | −0.24 (−1.7, 1.3) | 1.4 (0.60, 3.1) |
| BMI in 20s | n = 185 | n = 185 | n = 185 | n = 185 | n = 184 | n = 184 |
| Continuous | −0.01 (−0.14, 0.13) | 0.97 (0.84, 1.1) | −0.44 (−1.1, 0.23) | 1.1 (0.98, 1.2) | 0.08 (−0.10, 0.26) | 1.0 (0.94, 1.1) |
| ≥25 vs. <25 kg/m2 | −0.38 (−1.3, 0.54) | 1.4 (0.54, 3.6) | −5.2 (−9.9, −0.63) | 2.4 (1.3, 4.4) | −0.23 (−1.5, 1.0) | 1.9 (0.94, 3.8) |
| BMI in 30s | n = 185 | n = 185 | n = 185 | n = 185 | n = 184 | n = 184 |
| Continuous | −0.06 (−0.16, 0.05) | 0.95 (0.84, 1.1) | −0.30 (−0.84, 0.23) | 1.1 (0.99, 1.1) | 0.02 (−0.12, 0.17) | 1.0 (0.97, 1.1) |
| ≥25 vs. <25 kg/m2 | 0.04 (−0.90, 0.98) | 0.89 (0.34, 2.3) | 0.02 (−4.7, 4.8) | 1.4 (0.73, 2.6) | 0.76 (−0.50, 2.0) | 1.2 (0.59. 2.5) |
| Current BMI | n = 189 | n = 189 | n = 189 | n = 189 | n = 188 | n = 188 |
| Continuous | −0.10 (−0.10, 0.08) | 0.92 (0.83, 1.0) | −0.30 (−0.75, 0.15) | 1.0 (0.98, 1.1) | 0.06 (−0.06, 0.18) | 1.0 (0.97, 1.1) |
| ≥25 vs. <25 kg/m2 | 0.13 (−0.96, 1.2) | 0.45 (0.16, 1.2) | 0.38 (−5.1, 5.8) | 1.3 (0.60, 2.6) | 0.92 (−0.51, 2.4) | 1.2 (0.51, 2.6) |
a
Square-root transformed.
b
Adjusted for bw/ga and abstinence time.
c
Additionally adjusted for age (days) at examination.