Table 1.
miRNAs that promote chemoresistance |
miRNAs that promote chemosensitivity |
||
---|---|---|---|
miRNA | Target gene | miRNA | Target gene |
miR-21[20,21] | PTEN,[20] RECK[20] | miR-34[26,27] | Notch,[27] BCL2[27] |
miR-320a[22] | PDCD4[22] | miR-205[28] | ZEB1[28] |
miR-221–3p[23] | RB1[23] | miR-200[29] | ZEB1[29] |
miR-106a[24] | TP53INP1[24] | miR-506[30,31] | SPHK1,[30] PIM3[31] |
miR-155[25] | TP53INP1[25] | miR-15a[32,33,44] | WNT3A,[32] FGF7,[32] BMI-1,[33,44] Wee1,[44] Chk1,[44] Yap-1[44] |
Chk1 = checkpoint kinase 1, miRNA = microRNA.