Table 2:

Metabolic data of light-deprived mice in a type 1 diabetes model.

	12 hr ON: 12 hr OFF (Control)		24 hr OFF (Light-Deprived)
	Non-diabetic Vehicle	Diabetic Streptozotocin	Non-diabetic Vehicle	Diabetic Streptozotocin
n	11	8	12	9
Body Weight, g, 2 months (Pre-Injection)	22.4 (1.3)	19.9 (0.7)	21.2 (0.8)	20.7 (0.7)
Body Weight, g, 4 months (at randomization)	24.9 (1.4)	21.4 (0.2)*	24.1 (0.6)	21.6 (0.5)
Body Weight, g, 6 months (at assay)	25.3 (1.3)	22.3 (0.3)	24.8 (0.5)	22.7 (0.6)
Random Plasma Glucose, mg/dL, 2 months (Pre-Injection)	127.0 (3.5)	149.3 (33.1)	139.4 (25.9)	118.5 (10.5)
Random Glucose (mg/dL), 4 months (at randomization)	152.2 (10.3)	550.5 (29.0)****	159.0 (6.1)	521.3 (18.9)****
Random Glucose (mg/dL), 6 months (at assay)	156.9 (15.9)	525.0 (15.6)****	146.4 (13.0)	545.1 (12.3)****

Measures were taken at the time of diabetes induction, at time of randomization to control lighting or light-deprivation, and at the time of assay. Data are represented as mean (SEM) and groups were compared by 1-way (for GTT AUC and Fasting Insulin) or 2-way (for body weight and glucose) ANOVA with Bonferroni post-hoc correction.

^*= P<0.05

^****= P<0.0001 compared to healthy controls within same lighting group; P>0.05 for all other comparisons.