. Author manuscript; available in PMC: 2021 Apr 1.

Published in final edited form as: Neurobiol Dis. 2020 Jan 21;137:104754. doi: 10.1016/j.nbd.2020.104754

Table 3:

Metabolic data of mice with disrupted rod phototransduction in a type 1 diabetes model.

	Non-Diabetic (Vehicle)			Diabetic (Streptozotocin)

	Wild Type	gnat1−/−	rpe65−/−	Wild Type	gnat1−/−	rpe65−/−
n	10	9	9	8	8	7
Fasting Plasma Glucose, mg/dL, 2 months (Pre-Injection)	112.2 (5.7)	112.7 (10.7)	106.2 (9.9)	100.0 (7.3)	104.3 (2.9)	93.3 (9.7)
Fasting Plasma Glucose (mg/dL), 3 month (Post-Injection)	115.2 (8.3)	127.8 (13.5)	112.8 (7.8)	500.2 (38.4)^****	520.9 (15.4)^****	539.5 (44.9)^****
Fasting Plasma Glucose (mg/dL), 6 months (at assay)	129.8 (7.7)	135.2 (7.8)	120.0 (11.8)	565.4 (16.4)^****	547.1 (29.2)^****	580.7 (15.9)^****

Data are represented as mean (SEM) and groups were compared by 2-way ANOVA with Bonferroni post-hoc correction.

^****

= P<0.0001 compared to healthy controls with same genotype; P>0.05 for all other comparisons.