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. 2020 Feb 12;22(2):e16932. doi: 10.2196/16932

Table 3.

Sensitivity and specificity by applying the same cut-off points for the draft algorithm with and without EDSS.a

Draft algorithm Cut-off Sensitivity Specificity
SPMS versus transitioning and RRMS (upper cut-off)

With EDSS >57.8 0.82 0.81

Without EDSS
0.79 0.74
RRMS versus transitioning and SPMS (lower cut-off)

With EDSS <46.3 0.72 0.89

Without EDSS
0.76 0.86

aEDSS: Expanded Disability Status Scale; RRMS: relapsing-remitting multiple sclerosis; SPMS: secondary progressive multiple sclerosis.