Table 3. Frequency of severe dengue categories comparing children (< 15 years) versus adults and Asia versus Latin America.
| Overall | Asia & Latin America | Asia | Latin America | ||||
|---|---|---|---|---|---|---|---|
| < 15 years | > = 15 years | < 15 years | > = 15 years | < 15 years | > = 15 years | ||
| Non-Severe | 1463 (84.4%; 82.1–86.1) | 878 (82.7%; 80.3–84.9) | 585 (87.1%; 84.3–89.5) | 745 (83.0%; 80.4–85.5) | 524 (86.8%; 83.8–89.4) | 133 (80.6%; 73.7–86.3) | 61 (89.7%; 79.9–95.8) |
|
Severe Male* Female* |
271 (15.6%; 13.9–17.4) 129 (14.0%; 11.8–16.4) 142 (17.5%; 15.0–20.3) |
184 (17.3%; 15.1–19.7) 88 (15.8%; 12.8–19.1) 96 (19.1%; 15.7–22.8) |
87 (12.9%; 10.5–15.7) 41 (11.2%; 8.2–14.9) 46 (15.0%; 11.2–19.5) |
152 (17.0%; 14.5–19.6) 71 (15.1%; 12.0–18.7) 81 (19.0%; 15.4–23.0) |
80 (13.2%; 10.6–16.2) 41 (12.5%; 9.1–16.6) 39 (14.1%; 10.2–18.7) |
32 (19.4%; 13.7–26.3) 17 (19.3%; 11.7–29.1) 15 (19.5%; 11.3–30.1) |
7 (10.3%; 4.2–20.1) 0 7 (24.1%; 10.3–43.5) |
|
Plasma Leakage** Clinical shock*** Fluid accumulation with respiratory distress*** |
244 (90.0%; 85.8–93.3) 210 (77.5%; 72.0–82.2) 79 (29.2%; 23.8–35.0) |
173 (94.0%; 89.6–97.0) 147 (79.9%; 73.4–85.4) 68 (37.0%; 30.0–44.4) |
71 (81.6%; 61.8–81.5) 63 (72.4%; 61.8–81.5) 11 (12.6%; 6.5–21.5) |
144 (94.7%; 89.9–97.7) 120 (78.5%; 72.6–85.1) 55 (36.2%; 28.6–44.4) |
71 (88.8%; 79.7–94.2) 63 (78.8%; 68.2.-87.1) 11 (13.8%; 7.1–23.3) |
29 (90.1%; 75.0–98.0) 27 (84.4%; 76.2–94.7) 13 (40.6%; 23.7–59.4) |
0 0 0 |
| Bleeding** | 39 (14.4%; 10.4–19.1) | 22 (12.0%; 7.6–17.5) | 17 (19.5%; 11.8–28.4) | 19 (12.5%; 7.7–18.8) | 13 (16.3%; 8.9–26.2) | 3 (9.4%; 19.8–25.0) | 4 (57.1%; 18.4–90.1) |
| Organ Dysfunction** | 28 (10.3%; 7.0–13.6) | 24 (13.0%; 8.5–18.8) | 12 (13.8%; 7.3–22.9) | 12 (7.9%; 4.1–13.4) | 9 (11.3%; 5.3–20.3) | 4 (12.5%; 3.5–29.0) | 3 (42.9%; 9.9–81.6) |
| Total | 1734 | 1062 | 672 | 897 | 604 | 165 | 68 |
Numbers represent frequencies (%; 95% confidence interval).
Numbers in the severity categories include overlapping cases.
Numbers in bold indicate statistically significant differences between age groups (non-overlapping 95% CI).
* Percentages refer to the number of male / female patients for the respective category in the denominator.
** Percentages refer to the overall number of severe patients in the denominator.
*** Percentages in the severe categories refer to the number of severe patients for the respective category in the denominator.