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. 2020 Mar 4;15(3):e0229344. doi: 10.1371/journal.pone.0229344

Table 3. Multivariate analysis using Cox regression for association between evolution of chronic kidney disease and omeprazole and ARBs use in patients followed-up at the nephrology ambulatory clinic of the Municipal Polyclinic of Divinópolis-MG, Brazil, 2016–2017 (n = 199).

Variables Hazard Ratio (HR) Confidence Interval (95% CI) p-value
Omeprazole use
Non-users (reference category) 1.00 - -
Users 7.34 3.94–13.71 < 0.001*
ARBs use
Non-users (reference category) 1.00 - -
Users 0.60 0.37–0.96 0.033*

* p-value < 0.05