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. 2020 Mar 4;15(3):e0229696. doi: 10.1371/journal.pone.0229696

Table 1. Baseline characteristics of the study population.

Characteristics N = 200
Age, year, mean ± SD 59.7 ± 9.2
Sex, male 182 (91.0%)
Etiologies of liver disease
 Alcohol 24 (12.0%)
 HBV 137 (68.5%)
 HCV 17 (8.5%)
 Others 22 (11.0%)
Laboratory findings
 Platelet count§, x1000/mm3 163.0 [116.5–206.5]
 Serum albumin§, g/dL 3.5 [3.2–3.8]
 Bilirubin§, mg/dL 0.6 [0.5–0.9]
 Prothrombin time§, % 86.1% [77.3%-95.1%]
 INR§ 1.1 [1.0–1.1]
 ALT§, IU/L 35 [24–53]
Child-Pugh score
 5–6 178 (89.0%)
 7–8 22 (11.0%)
MELD score 7 [7–9]
Number of tumors
 1 39 (19.5%)
 2 49 (24.5%)
 3 31 (15.5%)
 ≥4 81 (40.5%)
Tumor size, mean ± SD, cm
 Largest 6.8 ± 4.3
 Second largest 2.6 ± 2.3
 Third largest 1.5 ± 0.8
Outside Milan criteria 200 (100.0%)
Up to seven criteria
 Within up-to-seven criteria 48 (24.0%)
 Beyond up-to-seven criteria 152 (76.0%)
Alpha-fetoprotein, ng/mL
 Median 49.5 [10.0–508.0]
 ≤200 66 (33.0%)
 >200 134 (67.0%)

161 patients with multiple tumors

112 patients with number of tumors >2

§Numbers are presented as median and numbers in brackets are the interquartile ranges

HBV: hepatitis B virus, HCV: hepatitis C virus, SD: standard deviation