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. 2020 Feb 21;16(2):e1008330. doi: 10.1371/journal.ppat.1008330

Fig 1. Species-dependent support of ANP32A or ANP32B for Influenza A viral replication.

Fig 1

Vectors carrying 20 ng of ANP32A or ANP32B proteins, or empty vectors, were co-transfected into DKO cells, together with a minigenome reporter, a Renilla expression control, and influenza virus polymerases from either avian influenza H7N9ZJ13 (A) or H9N2ZJ12 (B); human influenza WSN (C); swine influenza H1N1NC08 (D); canine influenza H3N2GD11 (E); or equine influenza H3N8XJ07 (F). Luciferase activity was measured 24 h later. (Data are Firefly activity normalized to Renilla, Statistical differences between cells are labeled according to a one-way ANOVA followed by a Dunnett’s test; NS = not significant, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. The results represent at least three independent experiments.) ch, chicken; hu, human; sw, swine; eq, equine; ca, canine.