Metabolic pathways enriched by significant features (raw P < 0.05) associated with p,p’-DDT, o,p’-DDT and p,p’-DDE concentrations. Circles are colored by the similarity between the chemicals: Dark red (group 1) indicates the most common pathways shared by all three chemical exposure and dark blue (group 3) indicates unique pathway found with p,p’-DDE only. Size of circles is proportional to the overlap size (i.e. number of significant metabolites in each pathway, ranging 3–13).