Selected metabolite levels in the Child Health and Development Studies (CHDS) subjects categorized by quartile 1 and 4 of p,p’-DDT (A) and p,p’-DDE (B) serum levels. The significant association of represented amino acid metabolites with p,p’-DDT exposure, and lipid metabolites with p,p’-DDE exposure are presented. A: proline and serine, adduct M(C13)+H, confirmed by accurate m/z match and co-elution with standard; phosphoserine, adduct M+Na, high confidence feature by isotope clustering; B: phosphotidyl serine and dimethylheptanoyl carnitine, adduct M+H, high confidence feature by isotope clustering; linoleate, adduct M+Na, confirmed by accurate m/z match and co-elution with standard. *P < 0.05, #P =0.07, by student’s t test comparing Q1 and Q4.