Table 3.
Comparison of participants with urologic chronic pelvic pain syndrome (UCPPS) with and without non-urological chronic overlapping pain conditions (COPC) with the COPC control group on urological, non-urological pain, and psychological symptoms and traits.
| UCPPS+COPC (n=162) | UCPPS Only (n=262) | COPC (n=200) | UCPPS+COPC vs UCPPS Only* | UCPPS+COPC vs COPC* | UCPPS Only vs COPC* | ||||
|---|---|---|---|---|---|---|---|---|---|
| Mean (SD) | Mean (SD) | Mean (SD) | p | d | p | d | p | d | |
| Urological Symptoms** | |||||||||
| SYM-Q Pain (0–10) | 5.6 (2.2) | 4.7 (2.1) | 1.4 (2.2) | .002 | 0.32 | <.001 | 2.05 | <.001 | 1.75 |
| SYM-Q Urgency (0–10) | 5.4 (2.6) | 4.8 (2.5) | 2.3 (2.5) | .1 | 0.16 | <.001 | 1.30 | <.001 | 1.18 |
| SYM-Q Frequency (0–10) | 5.5 (2.6) | 4.6 (2.6) | 2.3 (2.8) | .003 | 0.31 | <.001 | 1.21 | <.001 | 0.95 |
| GUPI Pain (0–23) | 13.9 (4.6) | 11.7 (4.1) | 3.3 (4.5) | <.001 | 0.42 | <.001 | 2.41 | <.001 | 2.14 |
| GUPI Urinary (0–10) | 6.0 (3.1) | 4.9 (2.8) | 2.4 (2.5) | .002 | 0.32 | <.001 | 1.34 | <.001 | 1.04 |
| GUPI quality of Life Impact (0–12) | 8.3 (2.8) | 7.4 (2.9) | 3.0 (3.2) | .02 | 0.25 | <.001 | 1.87 | <.001 | 1.69 |
| GUPI Total (0–45) | 28.2 (8.8) | 24.0 (8.1) | 8.7 (8.9) | <.001 | 0.41 | <.001 | 2.31 | <.001 | 2.01 |
| ICINDEX Symptom (0–20) | 11.0 (4.6) | 9.0 (4.6) | 4.4 (4.0) | .003 | 0.32 | <.001 | 1.64 | <.001 | 1.23 |
| ICINDEX Problem (0–16) | 9.6 (4.2) | 7.9 (4.4) | 3.3 (4.0) | .004 | 0.31 | <.001 | 1.64 | <.001 | 1.27 |
| AUA Symptom Index (0–35) | 17.8 (9.1) | 14.0 (7.8) | 6.8 (7.2) | <.001 | 0.36 | <.001 | 1.44 | <.001 | 1.12 |
| Non-urologic Pain Symptoms** | |||||||||
| BPI Pain Severity (0–10) | 4.6 (2.0) | 3.7 (1.9) | 3.3 (2.3) | <.001 | 0.36 | <.001 | 0.68 | <.001 | 0.42 |
| BPI Pain Interference (0–10) | 4.7 (2.9) | 3.2 (2.5) | 3.3 (2.7) | <.001 | 0.40 | <.001 | 0.59 | .07 | 0.19 |
| Body Map # of sites checked (0–45) | 9.0 (8.6) | 3.8 (3.5) | 11.8 (11.1) | <.001 | 0.73 | .04 | −0.23 | <.001 | −0.91 |
| CMSI Sum of Symptoms (0–39) | 15.9 (8.4) | 8.4 (4.9) | 11.7 (9.2) | <.001 | 1.06 | <.001 | 0.57 | .005 | −0.29 |
| Psychological Symptoms & Traits** | |||||||||
| HADS Anxiety (0–21) | 8.9 (4.7) | 6.9 (4.3) | 7.6 (4.9) | <.001 | 0.42 | .02 | 0.26 | .23 | −0.12 |
| HADS Depression (0–21) | 6.6 (4.6) | 4.6 (3.7) | 5.5 (4.6) | <.001 | 0.40 | .02 | 0.27 | .27 | −0.11 |
| PANAS Positive Affect (5–50) | 28.1 (7.7) | 30.9 (7.4) | 29.0 (8.6) | .009 | −0.27 | .13 | −0.17 | .48 | 0.07 |
| PANAS Negative Affect (5–50) | 23.6 (8.8) | 19.6 (7.2) | 20.0 (7.9) | <.001 | 0.42 | <.001 | 0.45 | .72 | 0.04 |
| PSS (0–40) | 19.0 (8.4) | 14.9 (7.2) | 17.3 (8.0) | <.001 | 0.43 | .03 | 0.25 | .07 | −0.19 |
| CSQ Catastrophizing (0–36) | 14.4 (9.2) | 11.4 (8.4) | 9.5 (7.7) | .04 | 0.22 | <.001 | 0.62 | <.001 | 0.43 |
| IPIP Neuroticism (24–120) | 67.1 (17.8) | 60.1 (15.6) | 64.9 (17.1) | <.001 | 0.36 | .38 | 0.10 | .06 | −0.19 |
| IPIP Extraversion (24–120) | 78.7 (13.6) | 81.4 (13.9) | 78.4 (14.8) | .18 | −0.14 | .84 | 0.02 | .25 | 0.12 |
Analyses adjusted for age, sex, race, and employment status.
Numbers in parentheses refer to the range of possible scores.
SYM-Q = Symptom and Health Care Utilization Questionnaire; GUPI = Genitourinary Pain Index; ICINDEX = Interstitial Cystitis Symptom Index and Problem Index; AUA = American Urological Association; BPI = Brief Pain Inventory; CMSI = Complex Multi-Symptom Inventory; HADS = Hospital Anxiety and Depression Scale; PANAS = Positive and Negative Affect Schedule; PSS =Perceived Stress Scale; CSQ = Coping Strategies Questionnaire; IPIP = International Personality Item Pool.