fig 3.

Infant, imaged at ages 10 weeks, 4 months, and 8 months.

A, Axial SE T1-weighted MR image (500/13/2) at 10 weeks: pachygyric left frontoparietal cortical tuber is less hyperintense than semilunar deep white matter “rim” of transmantle dysplasia (short arrows), which extends all the way to the wall of the lateral ventricle; overlying subarachnoid space is enlarged; various linear white matter anomalies (only two marked by long arrows) are present in both hemispheres; and small subependymal nodules are seen along cellae mediae of both lateral ventricles (not marked).

B, Axial CT scan at 4 months: periphery of transmantle dysplasia is densely calcified, strands of “sunburst” pattern extend toward cortex and left lateral ventricle (not marked); left parietal white matter anomalies (long arrow) are faintly hyperdense; and small subependymal nodules can be seen, for example, in the right lateral ventricle (curved arrow).

C, Axial SE T1-weighted MR image (500/12/2) at 8 months: note that intensity pattern of transmantle dysplasia (not marked) has changed (compare with A); subependymal nodules are visible at cella media of left ventricle (not marked), but white matter anomalies are not visible.

D, Axial high-resolution (surface coil) FSE T2-weighted MR image (4000/112_eff/1) at 8 months: transmantle dysplasia is depicted as layered swirls of different signal intensity (arrows).