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. 1999 Oct;20(9):1584–1596.

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fig 1. — A and B, Test with a low (A) and high (B) threshold. The sensitivity and specificity of a test changes according to the threshold selected; hence, these diagnostic performance parameters are threshold-dependent. Sensitivity with a low threshold (TPa/diseased patients) is greater than sensitivity with a higher threshold (TPb/diseased patients). Specificity with a low threshold (TNa/nondiseased patients) is less than specificity with a high threshold (TNb/nondiseased patients). TP indicates true positive; TN, true negative; FP, false positive; FN, false negative.