Table 2. Serum chemistries exhibit similar nighttime changes in fed and fasted Ngfr-KO mice.
Serum was collected at ZT16 in 12–16 week old ad libitum fed mice or following a 16 hr overday fast. Data are presented as mean ± SEM. *p<0.05 compared to WT by Student’s t-test. #p<0.05 compared to fed state by Student’s t-test, exact p-values can be found in Table 2—source data 1. n = 8/group.
| Ngfr-WT | Ngfr-KO | ||
|---|---|---|---|
| ZT16 | |||
| Body Weight (g) | Fed | 29.4 ± 0.4 | 23.9 ± 0.5* |
| Fasted | 26.2 ± 0.5# | 23.3 ± 0.7* | |
| Glucose (mg/dl) |
Fed | 299 ± 13.0 | 312 ± 29.2 |
| Fasted | 145 ± 25.6# | 160 ± 13.6# | |
| Insulin (ng/ml) |
Fed | 2.0 ± 0.5 | 0.88 ± 0.2 |
| Fasted | 0.16 ± 0.1# | 0.03 ± 0.1# | |
| Ketones (mM) |
Fed | 0.1 ± 0.03 | 0.2 ± 0.11 |
| Fasted | 1.6 ± 0.10# | 1.4 ± 0.13# | |
| Leptin (ng/ml) |
Fed | 3.3 ± 0.9 | 1.5 ± 0.2 |
| Fasted | 0.8 ± 0.15# | 0.8 ± 0.12# | |
| Corticosterone (ng/ml) |
Fed | 123 ± 8.3 | 146 ± 8.5 |
| Fasted | 163 ± 8.2# | 176 ± 3.7# | |