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. 2020 Mar 4;40(3):BSR20193431. doi: 10.1042/BSR20193431

Figure 1. Effects of naringin on ox-LDL-induced HUVECs injury.

Figure 1

Naringin plays a protective role against ox-LDL-induced endothelial injury. Assessment of the dose–response effect of naringin (A) and ox-LDL (B) on cell viability, using the CCK-8 assay. (C and D) Representative results and assessment of the dose–response effect of naringin on cell viability in the presence or absence of ox-LDL (80 μg/ml). HUVECs were pretreated with various concentrations of naringin for 2 h, followed by incubation with ox-LDL (80 μg/ml) for 24 h; scale bars: 50 and 10 μm. (E) Assessment of the dose–response effect of naringin on LDH release in the presence or absence of ox-LDL (80 μg/ml). Data are presented as mean ± SD, n = 6, *P < 0.05, **P < 0.01, and ***P < 0.001 vs. the vehicle-treated control; ###P < 0.001 vs. the ox-LDL-induced cells.