Table 1.

The function of resveratrol in the cardiovascular system

Cell type	Function	Reference
Endothelial cells	Inflammation↓	(Berman et al., 2017), (Schwager, Richard, Widmer, & Raederstorff, 2017), (Sangwung et al., 2017), (Cicha et al., 2009)
	Endothelial function↑	(Wallerath et al., 2002), (Mattagajasingh et al., 2007), (Cheang et al., 2018), (Wong et al., 2013), (Magyar et al., 2012)
	Oxidative stress↓	(W. Zhang, Huang, et al., 2017; Y. Zhang, Wang, et al., 2017), (Liu et al., 2015), (Sangwung et al., 2017), (J. Li, Yu, Ying, Shi, & Wang, 2017), (Cheang et al., 2014)
	Autophagy↑	(Liu et al., 2015), (Vion et al., 2017)
	Elongation↑	(Cicha et al., 2011)
	Apoptosis↓	(J. Li et al., 2017)
	Mitochondrial mass↓	(Csiszar et al., 2009)
	Mitochondrial ROS↓	(Zhou et al., 2014)
	eNOS uncoupling↓	(Xia et al., 2010)
	Over‐proliferation↓	(Yao et al., 2013)
	Re‐endothelialization↑	(Yurdagul et al., 2014)
	Angiogenesis↓	(Fukuda et al., 2006), (Simão et al., 2012)
Vascular SMCs	Hyperplasia↓	(Poussier, Cordova, Becquemin, & Sumpio, 2005), (Thompson, Martin, & Rzucidlo, 2014), (Yurdagul et al., 2014), (Hwang et al., 2016)
	Differentiation↑	(Thompson et al., 2014)
	Senescence↓	(E. N. Kim, Kim, et al., 2018; T. T. Kim, Parajuli, et al., 2018)
	Fibrosis↓	(E. N. Kim, Kim, et al., 2018; T. T. Kim, Parajuli, et al., 2018)
	Migration↓	(Hwang et al., 2016)
Cardiomyocytes	Oxidative stress↓	(Y. Li et al., 2013), (Bagul, Deepthi, Sultana, & Banerjee, 2015), (Diao et al., 2018), (B. Wang et al., 2014)
	Cardiac hypertrophy↓	(Bagul et al., 2015), (Thandapilly et al., 2011), (Gélinas et al., 2018), (Ma et al., 2017), (Matsumura et al., 2018), (Gan et al., 2014)
	Apoptosis↓	(C. J. Chen et al., 2009), (Diao et al., 2018), (B. Wang et al., 2014), (Varma Penumathsa et al., 2006)
	Inflammation↓	(C. Zhang et al., 2012), (Planavila, Iglesias, Giralt, & Villarroya, 2011), (Gupta, DiPette, & Supowit, 2014)
	Mitochondrial elongation↓	(Ren et al., 2017)
	Mitochondrial biogenesis↑	(Biala et al., 2010), (Ma et al., 2017)
	Cardiac remodelling↓	(Biala et al., 2010)
	Dysfunctional autophagic flux↓	(B. Wang et al., 2014)
	Cardiac remodelling↑	(B. Wang et al., 2014)
	Cardiac fibrosis↓	(G. Wang, Song, Zhao, Li, & Liu, 2018), (Diao et al., 2018), (C. Chen et al., 2019)
	Ischaemia/reperfusion ischaemia↓	(Deng, Wang, He, Xu, & Xie, 2017)
	Autophagy↑	(B. Wang et al., 2014)
	Cardiac angiogenesis↑	(Fukuda et al., 2006)
Monocytes/macrophages	Inflammation↓	(Schwager et al., 2017), (S. Y. Park et al., 2017), (Buttari et al., 2014)
	M2 polarization↑	(S. Y. Park et al., 2017)
	Monocyte‐to‐macrophage differentiation↓	(Vasamsetti et al., 2016)
	Macrophage infiltration↓	(Gupta et al., 2014)
	Foam cell formation↓	(Dong et al., 2014), (Berrougui, Grenier, Loued, Drouin, & Khalil, 2009)