Figure 2: Regulation of core-clock elements by light signaling proteins.

(A) Transcriptional regulation of core-clock genes by photoreceptors or components of light signaling pathways. The presumed regulation is based on various sources of experimental evidence but does not include genetic data. Dot-ended lines represent protein-chromatin associations for which the biological role (i.e. transcriptional regulation) has not been described. Lines with blunt ends and arrows indicate repression and activation, respectively. Cyan lines and boxes indicate clockwork genes. Gray boxes group genes targeted by the same component.

(B) Protein-protein interactions between core-clock players and components involved in light perception or signaling. Cyan ovals indicate clockwork elements. Regulatory elements belonging to different light wavelength signaling cascades are represented with distinct colors: Red elements, red light; blue elements, blue light; green elements, regulatory players shared by different light wavelength perception pathways. Ovals represent proteins.