Table 1.
Baseline clinicopathologic characteristics of MIS versus open radical hysterectomy
| Variable | MIS N (%) | OPEN N (%) | P |
|---|---|---|---|
| N | 117 (59.7) | 79 (40.3) | |
| Approach | |||
| Robotic | 106 (90.6) | - | |
| Laparoscopic | 9 (7.7) | - | |
| Converted to open | 2 (1.7) | - | |
| Age, years Median (range) | 46 (28–71) | 44 (23–85) | 0.59 |
| BMI, kg/m2 Median (range) | 27.2 (17.7–51.5) | 25.9 (17.9–45) | 0.46 |
| FIGO 2009 Stage | 0.24 | ||
| IA1 with LVI | 2 (1.7) | 1 (1.3) | |
| IA2 | 12 (10.3) | 3 (3.8) | |
| IB1 | 103 (88) | 75 (94.9) | |
| Histology | 0.52 | ||
| SCC | 48 (41) | 26 (32.9) | |
| Adenocarcinoma | 65 (55.6) | 50 (63.3) | |
| Adenosquamous | 4 (3.4) | 3 (3.8) | |
| Clinical tumor size, cm Median (range) | 0 (0–4) | 0 (0–4) | 0.16 |
| Path tumor size, cm Median (range) | 1.6 (0.2–7.5) | 1.9 (0.4–8.6) | 0.17 |
| Tumor size | |||
| <=2 cm | 80 (74.1) | 52 (69.3) | 0.7 |
| >2 cm | 28 (25.9) | 23 (30.7) | |
| Margin positive | 2 (1.7) | 2(2.5) | 1.0 |
| LVI | 0.33 | ||
| Yes | 41 (35) | 35 (44.3) | |
| Suspicious | 6 (5.1) | 2(2.5) | |
| Node positive | 20 (17.1) | 23 (29.1) | 0.046 |
| Rt parametria area, cm2 Median (range) | 7.0 (0.44–34.20) | 6.5 (0.9–25.0) | 0.39 |
| Lt parametria area, cm2 Median (range) | 7.5 (0.84–22.75) | 7.3 (0.9–24.5) | 0.67 |
| Adjuvant therapy | 39 (33.3%) | 42 (53.2%) | 0.006 |
| No residual in hysterectomy | 29 (24.8%) | 8 (10.1%) | 0.01 |
MIS, minimally invasive surgery; BMI, body mass index; FIGO, International Federation of Gynecology and Obstetrics; LVI, lymphovascular invasion; SCC, squamous cell carcinoma