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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: Cancer Res. 2020 Jan 7;80(5):1102–1117. doi: 10.1158/0008-5472.CAN-19-2374

Figure 6. Iris silencing prevents TNBCs metastasis and enhances mice OS.

Figure 6.

(A-D) Representative images of indicated tumors, showing morphologically normal (arrowheads), mesenchymal-like cells (arrows), mitotic (asterisks) cells, necrosis (double-headed arrows) and infiltrated lymphocytes (arrows, D). (E-H) Lung metastasis, (I-L) liver metastasis, and (M-P) Kidney metastasis in mice injected with indicated cells. Scale bar=100μm (A, C, F, H, L, and N), 250μm (J, k Na M), and 500μm (B, D, E, G, I, O, and P). (Q) Overall survival in mice injected with 4T1/shCtrl cells (black) or 4T1/shIris2 cells (red).