Figure 1.

GAS5 and ABCB1 Expression Levels in Breast Cancer Tissues and Cells

(A) Heatmap of differentially expressed lncRNAs in MCF-7 and MCF-7/ADR cells (n = 3). (B) Heatmap of differentially expressed mRNAs in MCF-7 and MCF-7/ADR cells (n = 3). (C and D) GAS5 expression (C) and ABCB1 mRNA expression (D) in breast cancer tissues from responder and non-responder patients were detected by quantitative real-time PCR. (E) Negative correlation between GAS5 and ABCB1 expressions in breast cancer tissues. (F and G) GAS5 expression (F) and ABCB1 mRNA expression (G) in MCF-7 and MCF-7/ADR cells were detected by quantitative real-time PCR. (H) The ABCB1 protein expression in MCF-7 and MCF-7/ADR cells was detected by western blot analysis. Data are shown as the mean ± SD (n = 3). *p < 0.05, **p < 0.01 versus respective control.