FIGURE 8.
Virulence of isolates of serotypes 22F and 33F in a sepsis model of infection. (A) Colony counts expressed as Log10 CFU/ml from the blood of mice infected with M11 strain expressing serotype 22F (P244) or serotype 33F (P017) or with clinical isolates of serotypes 22F or 33F from pediatric origin (P) or adult origin (A). (B) Survival curves of P244 vs. P017 strains. (C) Survival curves of clinical isolates of serotype 33F from pediatric origin (P) or adult (A). Error bars represent standard deviations, and asterisks mark results that are statistically significant (two-tailed Student’s t-test: *P < 0.05; ***P < 0.001 for bacterial counts; and Log-rank test *P < 0.05; **P < 0.01 for survival curves).