TABLE 1.
Strains of S. pneumoniae used in this studya.
| Strain | Description/serotype (source)b ST/CCc | References/sourced |
| M11 | Non-encapsulated strain derived from R6 (Hex–, lytA+) | Domenech et al., 2014 |
| YNM2 | M11 transformant with DNA from strain 1734/19; serotype 8 | This study |
| 1734/19 | 8(blood) | SPRL |
| YNM3 | M11 transformant with DNA from strain 1732/19; serotype 11A | This study |
| 1732/19 | 11A(blood) | SPRL |
| YNM4 | M11 transformant with DNA from strain 1228/19; serotype 19A | This study |
| 1228/19 | 19A(blood) | SPRL |
| P007 | M11 transformant with DNA from strain 406; serotype 3 | Domenech et al., 2009 |
| P224 | M11 transformant with DNA from strain 3017/13; serotype 24F | Domenech et al., 2014 |
| P244 | M11 transformant with DNA from strain 3014/13; serotype 22F | Domenech et al., 2015 |
| 1407/18 | 22F(blood/pediatric) ST3134/CC1439 | SPRL |
| 1000/18 | 22F(blood/adult) ST13692/CC698 | SPRL |
| 1155/18 | 22F(CSF/pediatric) ST433/CC433 | SPRL |
| 523/18 | 22F(CSF/adult) ST13692/CC698 | SPRL |
| 223/11 | 22F(PF/pediatric) ST433/CC433 | SPRL |
| 1285/18 | 22F(PF/adult) ST698/CC698 | SPRL |
| 2780/17 | 22F(Otic/adult) ST13692/CC698 | SPRL |
| 100/08 | 22F(Otic/pediatric) ST433/CC433 | SPRL |
| 1766/18 | 22F(blood/pediatric) ST3134/CC1439 | SPRL |
| 2597/17 | 22F(blood/pediatric) ST433/CC433 | SPRL |
| 194/17 | 22F(blood/pediatric) ST433/CC433 | SPRL |
| 2153/17 | 22F(blood/pediatric) ST433/CC433 | SPRL |
| 212/18 | 22F(blood/adult) ST698/CC698 | SPRL |
| 250/18 | 22F(blood/adult) ST433/CC433 | SPRL |
| 306/18 | 22F(blood/adult) ST433/CC433 | SPRL |
| 613/18 | 22F(blood/adult) ST7314/CC433 | SPRL |
| P017 | M11 transformant with DNA from strain SSISP33F/1; serotype 33F | Domenech et al., 2015 |
| 1833/18 | 33F(blood/pediatric) ST717/CC717 | SPRL |
| 1950/18 | 33F(blood/adult) ST13320/CC717 | SPRL |
| 1088/16 | 33F(CSF/pediatric) ST717/CC717 | SPRL |
| 934/19 | 33F(CSF/adult) ST717/CC717 | SPRL |
| 800/18 | 33F(PF/pediatric) ST717/CC717 | SPRL |
| 363/18 | 33F(PF/adult) ST717/CC717 | SPRL |
| 782/15 | 33F(Otic/pediatric) ST1012/CC1012 | SPRL |
| 1945/15 | 33F(Otic/pediatric) ST717/CC717 | SPRL |
| 644/18 | 33F(blood/pediatric) ST717/CC717 | SPRL |
| 1018/18 | 33F(blood/pediatric) ST717/CC717 | SPRL |
| 1992/18 | 33F(blood/pediatric) ST4668/CC717 | SPRL |
| 2316/17 | 33F(blood/pediatric) ST13320/CC717 | SPRL |
| 1897/18 | 33F(blood/adult) ST717/CC717 | SPRL |
| 2027/18 | 33F(blood/adult) ST717/CC717 | SPRL |
| 627/18 | 33F(blood/adult) ST717/CC717 | SPRL |
| 840/18 | 33F(blood/adult) ST717/CC717 | SPRL |
aStrains are organized by serotype. bCSF, cerebrospinal fluid; PF, pleural fluid. cST, sequence type; CC, clonal complex. dSPRL, Spanish Pneumococcal Reference Laboratory.