Fig. 2.

Study schedule for CAPA-IVM and standard IVM (control). Patients were randomized to CAPA-IVM or standard IVM. The stimulation protocols are identical in the two arms. Patients received approximately 2.5 days of gonadotropin priming and no human chorionic gonadotropin (hCG) priming. CAPA-IVM group allocated patients had their oocytes 24-h longer in a prematuration culture (orange bar). All embryos were vitrified and transferred in subsequent cycles. CAPA, capacitation prematuration; D3, day 3; Gn, gonadotrophin; IVM, in vitro maturation; OCP, oral contraceptive pill; VIT, vitrification