Fig. 7.

Effect of ovariectomy and losartan on AT₁R mRNA expression in the BLA and HC. AT₁R mRNA expression was determined by real-time PCR. a BLA [Sham–Veh (n = 7), Ovx–Veh (n = 6), Sham–Los (n = 11), and Ovx–Los (n = 11). b Hc CA1 [Sham–Veh (n = 6), Ovx–Veh (n = 7), Sham–Los (n = 7), and Ovx–Los (n = 7). Los increased AT₁R mRNA regardless of surgery; p < 0.05 by two-way ANOVA (surgery, treatment) F = 4.74; DFn = 1; DFd = 23. c Hc CA3 [Sham–Veh (n = 6), Ovx–Veh (n = 9), Sham–Los (n = 9), and Ovx–Los (n = 11)]. Ovariectomy increased AT₁R mRNA regardless of treatment; *p < 0.05 vs Sham, same treatment (Student’s t test); p < 0.05 by two-way ANOVA (surgery, treatment) F = 4.79; DFn = 1; DFd = 31