. 2020 Feb 27;7:30. doi: 10.3389/fmolb.2020.00030

TABLE 2.

Cox proportional regression analysis in co-mutation of EGFR^L858R/TP53 on overall survival in LUAD.

Co-mutation type	Median, days	n.(event)	HR^a (95%CI)	P^a
EGFR^WT/TP53^WT	1653	246(76)	1.00
EGFR^WT/TP53^MUT	1229	224(81)	1.26(0.92–1.74)	0.156
EGFR^L858R/TP53^WT	1147	10(5)	1.77(0.71–4.40)	0.217
EGFR^L858R/TP53^MUT	719	11(7)	2.77(1.26–6.10)	0.012

HR^a(95%CI), Hazard ratios, 95% confidence intervals, adjusted by age, gender, and cancer stage; P^a, P-values, adjusted by age, gender, and cancer stage; EGFR^WT/L858R, rs1214568 genotype TT/TG in EGRF; TP53^WT/MUT, TP53 wild/mutant type.