Fig. 3.

Foot-shock experience is associated with enhanced regional connectivity in the ACC. A Schema of fMRI experimental design. B Thresholded maps of interaction effects based on a two-way repeated measures ANOVA. Yellow voxels indicate region with significant interaction effects (corrected P < 0.05). C The ACC was selected for simple effect analysis; purple voxels indicate the selected regions. D Simple effect analysis of the ReHo values in foot-shock-experienced and naïve rats on days 1 and 2. Data are presented as the mean ± SEM; *P < 0.05, non-parametric rank-sum test.