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. 2020 Feb 27;10:112. doi: 10.3389/fonc.2020.00112

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Copyright © 2020 Xi, Gao, Wu, Fang, Xu, Liu, Yang, Zhu, Zhao, Lai, Zhang, Zhang and Jiang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Ultrasound of a 42-year-old man who incidentally detected a thyroid nodule is shown. (A) Conventional ultrasonography (CUS) showed that there was a solid hypoechoic nodule with a regular margin in the isthmus of the thyroid. The nodule was of intermediate suspicion. (B) Color Doppler showed intranodular and peripheral vascularity. (C) The elastography score was 2, indicating that the nodule was soft. (D) Contrast-enhanced ultrasonography (CEUS) revealed heterogenous enhancement. The nodule was a papillary thyroid carcinoma (PTC) confirmed by histological pathology.