Table 2.
Comparison between responders and nonresponders at rituximab initiation
| Characteristic | Responders | Nonresponders | P |
|---|---|---|---|
| Age (yr) | 65.6 ± 10.2 | 68.6 ± 4.1 | 0.58 |
| eGFR (ml/min per 1.73 m2) | 19.2 ± 6.5 | 14.2 ± 9.3 | 0.27 |
| Serum albumin level (g/l) | 26.7 ± 5,2 | 21.5 ± 4.2 | 0.10 |
| Urinary protein level (g/d) | 10.8 ± 6.6 | 19.2 ± 6.7 | 0.05 |
| Urinary albumin level (g/d) | 7.1 ± 2.4 | 6.9 ± 2.3 | 0.88 |
| Urinary albumin-to-protein ratio (%) | 74.3 ± 8.2 | 55.2 ± 3.9 | <0.001 |
| Urinary IgG level (mg/mmol) | 63.3 ± 40.4 | 157.6 ± 68.0 | 0.01 |
| Urinary IgG-to-protein ratio (%) | 6.7 ± 2.8 | 11.3 ± 2.9 | 0.02 |
| Urinary α1M level (mg/mmol) | 23.0 ± 14.3 | 30.6 ± 20.3 | 0.46 |
| Urinary α1M-to-protein ratio (%) | 3.1 ± 1.8 | 2.3 ± 1.3 | 0.48 |
| Urinary RBP level (mg/mmol) | 11.1 ± 7.2 | 14.0 ± 5.6 | 0.50 |
| Urinary RBP-to-protein ratio (%) | 1.5 ± 1.5 | 1.0 ± 0.1 | 0.54 |
α1M, alpha-1 microglobulin; eGFR, estimated glomerular filtration rate (according to the Modification of Diet in Renal Disease formula); RBP, retinol binding protein.
Data presented as mean ± SD.