Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Feb 27;11:110. doi: 10.3389/fgene.2020.00110

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Mens, Maas, Klap, Weverling, Klatser, Brakenhoff, van Meurs, Uitterlinden, Ikram, Kavousi and Ghanbari

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Manhattan plots showing the association of miRNA-SNPs with T2D, CAD, and lipid traits. The association miRNA-related SNPs and cardiometabolic traits were examined using the publicly available GWAS data. We reported the most significantly associated miRNA of each SNP loci. The horizontal red line indicates the study significance threshold. (A) Manhattan plot showing the association of miRNA-SNPs with T2D in which 12 SNPs in 8 miRNAs passed the significant threshold. (B) Manhattan plot showing the association of miRNA-SNPs with CAD in which 13 SNPs in 9 miRNAs passed the significance threshold. (C) Manhattan plot showing the association of miRNA-SNPs with lipid traits in which 107 SNPs in 36 miRNAs passed the significant threshold. When SNPs were present in more traits, the most associated SNP was plotted.