Table 1.

Vasculogenic mimicry and its association with prognosis in cancer.

Number of patients (percentage VM+)	Association	p-value	References
331 (7.9%)	VM group tended to have a lower 60-month survival rate than the non-VM group	p = 0.071	(18)
	VM group tended to have a higher hematogenous metastases than the non-VM group	p = 0.059
90 (28.6%)	VM correlated with lymph node metastases	p = 0.004	(26)
	Histological grade	p < 0.001
	Nottingham prognostic index (NPI) (worse prognosis)	p < 0.001
	No correlated with the presence of:
	ER	p = 0.391
	PR	p = 0.321
	Her2	p = 0.114
	VM correlated with overall survival	p < 0.001
	And disease-free survival	p < 0.001
200 (30%)	VM and Osteopontin co-expression correlated with pathological complete response	p = 0.006	(27)
202 (16.8%)	VM presence was higher in TNBC vs. non TNBC	p = 0.003	(28)
	VM correlated with worst	p < 0.001
	Disease free survival and overall survival	p = 0.015
134 (30.6%)	VM presence was higher in TNBC vs. non TNBC	p = 0.004	(29)
100 (29%)	VM presence was higher in TNBC vs. non TNBC	p = 0.020	(30)
	VM correlated with poorer overall survival	p = 0.015
174 (24.7%)	VM presence was higher in TNBC vs. non TNBC	p = 0.044	(31)
120 (22.5%)	VM correlated with positive node status;	p = 0.027	(32)
	a higher tumor stage	p = 0.022
	and higher levels of HER2	p = 0.018
	VM did not correlate with ERalpha or PR status	p = 0.143