Table 4.
Effect of nonsynonymous single-nucleotide polymorphisms (SNPs) in glutathione transferase omega-1 coding region of Salmo salar.
Nucleotide accession number | Gene | Gene acronym | SNP | Amino acid change | SIFT score | Polyphen score | SIFT+Polyphen score |
---|---|---|---|---|---|---|---|
NM_001141472.1 | Glutathione transferase omega-1 | gsto-1 | c.205A>G | S26G | IV | E | 5 |
c.484T>C | S119P | IV | E | 5 | |||
c.499T>C | Y124H | I | D | 4 | |||
c.769A>C | T214P | II | D | 4 |
SIFT and POLYPHEN scores are indicated from which the risk is obtained to assess whether the amino acid change produces a variation at protein structural level giving a risk of 1–4, being 1 the higher impact risk. S, serine; G, glycine; P, proline; Y, tyrosine; H, histidine; T, threonine.