Table 1.
First Author (Year) | Study Period | Sample size (T/C n) | TNM Stage | Drug Delivery | TCM Duration | TCM Intervention | Paclitaxel Regimen | TRR (T/C n) |
---|---|---|---|---|---|---|---|---|
Chen (2009) | 2005–2007 | 34/33 | IIIb: 23/24; IV: 11/9 | Injection | 6w | Huachansu injection | TPF: PTX+PDD+5-FU | 15/12 |
Ge et al. (2014) | NR | 20/20 | Advanced stage | Orally | 8w | Jianpixiaozheng decoction | TS: PTX+S-1 | 10/9 |
Huang et al. (2018) | 2015–2016 | 50/50 | Advanced stage | Injection | 18w | Kanglaite injection + Jianpiyiqi decoction | TP: PTX+PDD | 35/20 |
Lai et al. (2018) | 2015–2018 | 30/30 | IV | Orally | 6w | Shenlingbaizhu decoction | TCF: PTX+CF+5-FU | NR |
Li N. J., et al (2016) | 2013–2014 | 25/25 | Advanced stage | Orally | 4w | Rg3+Shenyi capsule | TCF: PTX+CF+5-FU | 17/11 |
Li et al. (2010) | 2007–2009 | 42/40 | Advanced stage | Orally | 22d | Liujunzi decoction | TCF: PTX+CF+5-FU | 25/23 |
Li et al. (2016a) | 2012–2015 | 33/32 | IV | Injection | 8w | Fufangkushen injection + Yiqiyangwei decoction | PTX | 27/18 |
Li et al. (2016b) | 2014–2015 | 50/50 | Advanced stage | Orally | 8w | Shenlingbaizhu decoction | TS: PTX+S-1 | 27/22 |
Liao (2018) | 2015–2016 | 31/31 | Advanced stage | Injection | 4w | Kang'ai injection | PTX+CF | 27/19 |
Liu and Zhang (2009) | 2006–2008 | 30/30 | IIIb: 17/14; IV: 13/16 | Injection | 20d | Aidi injection | TPF: PTX+PDD+5-FU | 16/16 |
Meng (2019) | 2015–2016 | 50/50 | III: 34/36; IV: 16/14 | Injection | 12w | Fufangkushen injection | PTX | 35/15 |
Tan et al. (2013) | 2007–2011 | 40/46 | IV | Orally | 6w | Fufangbanmao capsule | PTX+5-FU+LV | 19/12 |
Xue and Mao (2017) | 2013–2015 | 45/45 | Advanced stage | Orally | 8w | Rg3 | TCF: PTX+CF+5-FU | 35/28 |
You and Huang (2009) | 2007–2008 | 22/24 | III:6/5; IV:16/19 | Orally | 24w | Fuzhenghewei liquid medicament | TP: PTX+PDD/TCF: PTX+CF+5-FU | 8/8 |
T, treatment group; C, control group; TNM, cancer staging system; NR, not reported; TCM, traditional Chinese medicine, TRR, tumor response rate; w, week; d, day; PTX, paclitaxel; PDD, cisplatin; 5-FU, 5-fluorouracil; CF, calcium folinate; LV, leucovorin.