Table 2.
Changes of MCT expression during progression from normal to tumor epithelium in humans.
| Cancer type | MCT1 | MCT2 | MCT4 | Ref. |
|---|---|---|---|---|
| Adrenocortical cancer | + | [152] | ||
| Brain cancer | + | + | [89], [160], [188], [190], [222] | |
| Breast cancer | (+) | + | [32], [54], [223] | |
| Cervix cancer | + | + | [33] | |
| Colorectal cancer | (+) | + | [34], [157], [229] | |
| Esophageal adenocarcinoma | + | + | [151] | |
| Gastric cancer | (+) | [153], [155] | ||
| Hepatocellular carcinoma | − | + | [31] | |
| Melanoma | + | + | [96] | |
| Oral squamous cell carcinoma | + | [162] | ||
| Prostate cancer | (+) | [35], [93] |
+, upregulation in all reported cases; (+), non-systematic upregulation; -, downregulation.