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. 2020 Feb 21;2020:2685305. doi: 10.1155/2020/2685305

Figure 2.

Figure 2

miR-215-5p mediated the protective effects of ADSCs-Exos on HG-induced migration of MPC5 cells. (a) The expression of EMT-related miRNAs including miR-215-5p, miR-879-5p, miRNA-217a-5p, miRNA-3066-5p, and miRNA-7a-5p was determined by qRT-PCR in HG-induced MPC5 cells with or without ADSCs-Exo treatment. (b) Cell migration was evaluated by Transwell assay in HG-induced MPC5 cells treated with ADSCs-Exo NC and ADSCs-Exo-miRNA inhibitors. (c) The number of migratory cells was counted by ImageJ software in different groups. (d) The expression of miR-215-5p was measured by qRT-PCR in HG-induced MPC5 cells treated with ADSCs-Exo NC and ADSCs-Exo-miR215-5p inhibitor. ∗P < 0.05; ∗∗P < 0.01.