Javed 1991.

Methods	Allocation: randomised. Blindness: double. Duration: 12 weeks.
Participants	Diagnosis: schizophrenia (DSM III). History: stabilised for 6 months on neuroleptics, involved in rehabilitation, duration ill ˜13 yrs. N = 45. Age: mean 50 yrs. Sex: 33M, 12F.
Interventions	1. Flupenthixol decanoate: dose 40 mg/IM, frequency biweekly. N = 18. 2. Fluphenazine decanoate: dose 25 mg/IM, frequency biweekly. N = 20.
Outcomes	Adverse effects ‐ general side effects (HDS, EPSE, SE Checklist). Unable to use ‐ Global Impression (CGI ‐ no SD). Mental state (BPRS no SD).
Notes	Authors contacted.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Mentions that patients received either of the drugs according to randomisation. No information about process of sequence generation given.
Allocation concealment (selection bias)	Unclear risk	Method of allocation concealment not described.
Blinding (performance bias and detection bias) All outcomes	Unclear risk	States it is a double‐blind comparative trial. No other information given.
Incomplete outcome data (attrition bias) All outcomes	High risk	Attrition was 15.55% out of reasons not related to the treatment. Number of participants dropping out of each arm of the study not clarified. There is no information how this was dealt with in the analysis.
Selective reporting (reporting bias)	High risk	Some outcomes of interest regarding Mental State and Global Impression were reported incompletely so cannot be entered in meta‐analysis.
Other bias	High risk	Authors thank Lundbeck & Co. for unclear reasons.