Skip to main content
. Author manuscript; available in PMC: 2020 Oct 15.
Published in final edited form as: Biochemistry. 2019 Oct 4;58(41):4169–4182. doi: 10.1021/acs.biochem.9b00735

Figure 4. The SSNs in Figure 2 colored using the unique colors assigned to the clusters/UniProt IDs in SSN240 (“isofunctional” SSN).

Figure 4.

The coloring of SSN120 (Panel A), SSN185 (Panel B), and SSN320 (Panel D) was accomplished using the BridgeDB Cytoscape app and the “UniProt ID-Color-Cluster Number” mapping table provided by the Color SSN utility for SSN240 (Panel C); this table associates each accession ID in the SSN with its cluster color and number. The color mapping allows easy determination of the origins/destinations of nodes when the alignment score is changed. For example, in SSN185 the clusters in SSN185 that share dehydratase functions but are segregated in SSN240 can be determined; also, in SSN320, the clusters that result from phylogenetic separation can be determined, e.g., from the red PFL cluster in SSN240.