Figure 5.

Electron microscopy of the two siblings in Family 3 (a, b, c for #17B630C2; d, e, f for #342E9543). In #17B630C2, three different abnormalities of central microtubules were observed: no central microtubules (a), one peripheral microtubule doublet transposed to the center of the axoneme with eight pairs of peripheral microtubules and no central microtubules (b), and two pairs of central microtubules (c). In #342E9543, peripheral microtubules were disarranged with no central microtubules (d, e) and numerous microtubule singlets were observed (f)